San Francisco 49ers vs. St. Louis Rams: Spread Analysis and Pick Prediction

San Francisco continues to suffer from Super Bowl Loss Hangover Syndrome, and its offense has been inexplicably bad (10 points in two games). But they are the far superior team to the Rams, and the point spread is very tempting for 'Niner backers.

Point spread: The 49ers opened as three-point favorites; the total was sitting at 42 early Tuesday (Line updates and Matchup report).

OddsShark.com computer says: 12-9, Rams

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