San Francisco 49ers: 5 Things to Watch in Week 5 Against the Bills

At the quarter-turn of the 2012 NFL regular season, the San Francisco 49ers have had a mix of surprises to go along with realized expectations.

The Niners weren't supposed to beat the Super Bowl favorite Green Bay Packers at Lambeau Field in Week 1.

The Week 2 "Handshake Game" versus the Detroit Lions had little fireworks beyond the pregame pyrotechnics that kicked off the Candlestick schedule en route to a home-opening victory for the Red and Gold.

San Francisco's midseason minicamp ...

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