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NFL Picks Week 12: Thanksgiving Football 2010, Predictions for Every NFL Game

Happy Thanksgiving! Let's enjoy a day of Thanksgiving Football 2010!

Here are my picks for all 16 games for Week 12 of the 2010 NFL season. 

You'll see some interesting selections, including my thoughts on whether the New Orleans Saints can end the Dallas Cowboys glimpse of promise today.

Moreover, will Philip Rivers' Chargers be able to take on Peyton Manning's Colts? Will the 49ers keep their playoff hopes alive with a win against the Cardinals on Monday Night Football? 

Find out my predictions on that, and much more.  

Last Week: 11-5

Cumulative Season Record: 90-70 (.563)

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Bleacher Report - San Francisco 49ers
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