Monday Night Football: 49ers Lose To the Defending Champion Saints, 25-22

What could have been one of the greatest games of Alex Smith's career with the San Francisco was all for not. He outplayed Drew Brees and if not for mistakes again by Jimmy Raye and Mike Singletary the 49ers would have come out on top over the defending champions the New Orleans Saints, but instead it's a 25-22 loss. 

The first quarter was a gift to the Saints as on the third play from scrimmage David Baas the cente...

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