Bills vs. 49ers: Spread Info, Line and Predictions

After being thoroughly trounced by the New England Patriots last week by a score of 52-28, things don't get any easier for the Buffalo Bills, as they have to travel across the country to take on the San Francisco 49ers.

The 49ers put a beating on another AFC East opponent last week, embarrassing the New York Jets by a score of 34-0.

With the 49ers' confidence growing and returning home after spending three of the first four weeks of the 2012 season on the road, it cou...

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