5 Bold Predictions for San Francisco 49ers’ Week 6 Matchup Against Cardinals

Points will be at a premium when the San Francisco 49ers and Arizona Cardinals square off on Sunday. 

Both teams are coming off their best defensive performances of the season, and four of the following five bold predictions are positive for the defenses. 

The 49ers (3-2) desperately need to win this game to pass Arizona (3-2) in the standings and keep pace with the Seattle Seahawks. San Francisco should be in good shape if the majority of these projections come to fruition. 

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